By Kasugai, Yu; Machtoub, Lina
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Additional info for Amyotrophic lateral sclerosis : advances and perspectives of neuro-nanomedicine
Cyanobacteria from soil and water samples collected around the world produce BMAA, giving rise to speculative biomagniﬁcation in food chains. Scientists have also found that newborn rats treated with BMAA show early neurotoxicity and impaired learning and memory as adults. 6 Are Toxins in Seafood Causing ALS? What started as the discovery of an unknown disease in Guam has spread to a line of ominous ﬁndings about some of our machtoub–ALS October 23, 2015 12:42 PSP Book - 9in x 6in Are Toxins in Seafood Causing ALS?
Mild abnormalities of electronystagmography machtoub–ALS 53 October 23, 2015 12:42 PSP Book - 9in x 6in 54 Diagnostic Criteria of Amyotrophic Lateral Sclerosis Electrophysiological features that are inconsistent with the diagnosis of ALS or suggest the presence of additional disease processes include one or more of the following: 1. focal reduction in compound muscle action potential or more than 10% in a 4 cm segment 2. motor conduction velocities, F-wave latencies, or H-wave amplitudes which are more than 30% above established normal values 3.
2003;304:1–7. 4. Yase Y. The pathogenesis of amyotrophic lateral sclerosis. Lancet. 1972;2:292–296. 5. Fang F, Kamel F, Lichtenstein P, et al. Familial aggregation of amyotrophic lateral sclerosis. Ann Neurol. 2009;66:94–99. 6. Sreedharan J, Blair IP, Tripathi VB, et al. TDP-43 mutations in familial and sporadic amyotrophic lateral sclerosis. Science. 2008; 319(5870):1668–1672. 7. Brugman F, Veldink JH, Franssen H, et al. Diﬀerentatiion of hereditary spastic paraparesis from primary lateral sclerosis in sporadic adultonset upper motor neuron syndromes.
Amyotrophic lateral sclerosis : advances and perspectives of neuro-nanomedicine by Kasugai, Yu; Machtoub, Lina